Giant radioactive mutant spiders are attacking the planet. It's up to you and your nuclear missiles to save the world. Try to score as many direct hits on the spiders so you don't run out of missiles (and so you don't inadvertently wipe out any cities). Keep in mind that the spiders learn from their experiences with you and get tougher and tougher to hit. Good luck, Missile Commander... the future of all mankind is in your hands!